发明名称 CO-CRYSTALS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME
摘要 The invention relates to compositions and co-crystals each comprising VX-950 and a co-crystal former selected from the group consisting of 4-hydroxybenzoic acid, 4-amino salicylic acid, phenylalanine, threonline, tartaric acid, adipic acid, succinic acetate, proline, methyl 4-hydroxybenzoate, anthranilic acid, and d-Biotin. Also within the scope of this invention are methods of making and using the same.
申请公布号 KR20090115970(A) 申请公布日期 2009.11.10
申请号 KR20097020031 申请日期 2008.02.27
申请人 VERTEX PHARMACEUTICALS INCORPORATED 发明人 CONNELLY PATRICK R.;KADIYALA IRINA;STAVROPOLUS KATHY;ZHANG YUEGANG;JOHNSTON STEVE;BHISETTI GOVINDA RAO;JURKAUSKAS VALDAS;ROSE PETER
分类号 C07D403/12;A61K31/497;A61K38/07;A61P31/12 主分类号 C07D403/12
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