摘要 |
FIELD: chemistry. ^ SUBSTANCE: invention relates to an improved highly-selective method of producing deserpidine (Ia) through demethylation of 11-methoxy group of 11-O-methyl reserpic acid lactone, with subsequent stages for reduction, hydrolysis and esterification of the obtained methyldeserpidate 3,4,5-trimethoxybenzoic acid. Output is 40%. ^ EFFECT: method for semisynthesis of deserpidine is described. ^ 6 cl, 7 ex |