| 发明名称 |
Synthesis of UDP-glucose: N-acylsphingosine glucosyltransferase inhibitors |
| 摘要 |
Disclosed is a novel enantiomeric synthesis ceramide-like inhibitors of UDP-glucose: N-acylsphingosine glucosyltransferase. Also disclosed are novel intermediates formed during the synthesis.
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| 申请公布号 |
US7615573(B2) |
申请公布日期 |
2009.11.10 |
| 申请号 |
US20070702425 |
申请日期 |
2007.02.05 |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN;GENZYME CORPORATION |
发明人 |
SIEGEL CRAIG;SHAYMAN JAMES A.;NELSON CAROL A.;HARRIS DAVID J.;COPELAND DIANE P. |
| 分类号 |
A61K31/40;C07D295/12;A61K31/4025;A61K31/445;A61K31/5375;A61P1/16;A61P7/06;A61P17/02;A61P25/28;A61P27/02;A61P35/00;A61P43/00;C07B53/00;C07B61/00;C07D295/18;C07D295/185;C07D319/18;C07D405/06;C07D498/04 |
主分类号 |
A61K31/40 |
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