发明名称 Nucleoside analogues and oligonucleotide derivative comprising nucleotide analogue thereof
摘要 A nucleotide analogue compound represented by formula (1) and salts thereof. In formula (1), A represents a direct bond, C1-4 alkylene, etc.; B represents an optionally substituted aromatic heterocyclic groups; and R1, R2, R3 and R4 each represents hydrogen, an amino-protecting group, a hydroxyl-protecting group, a phosphate group, or -P(R7)R8, wherein R7 and R8 each represents hydroxyl, protected hydroxyl, mercapto, protected mercapto, etc. The compounds are useful as nucleotide analogues for producing oligonucleotide analogues useful in an antisense method and for producing intermediates thereof.
申请公布号 US7615619(B2) 申请公布日期 2009.11.10
申请号 US20050504165 申请日期 2005.05.23
申请人 TAKESHI IMANISHI 发明人 IMANISHI TAKESHI;OBIKA SATOSHI
分类号 C07H21/00;C07H19/06;C07H19/10;C07H19/16;C07H19/20 主分类号 C07H21/00
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