发明名称 |
Heterocyclic modulators of PKB |
摘要 |
The invention relates to heterocyclic compounds of Formula I and compositions thereof useful for treating diseases mediated by protein kinase B (PKB) where the variables have the definitions provided herein. The invention also relates to the therapeutic use of such compounds and compositions thereof in treating disease states associated with abnormal cell growth, cancer, inflammation, and metabolic disorders.
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申请公布号 |
US2009275592(A1) |
申请公布日期 |
2009.11.05 |
申请号 |
US20080218754 |
申请日期 |
2008.07.16 |
申请人 |
AMGEN INC. |
发明人 |
ZENG QINGPING;ZHANG DAWEI;YAO GUOMIN;WOHLHIETER GEORGE E.;WANG XIANGHONG;RIDER JAMES;REICHELT ANDREAS;MONENSCHEIN HOLGER;HONG FANG-TSAO;FALSEY JAMES R.;DOMINGUEZ CELIA;BOURBEAU MATTHEW P.;ALLEN JOHN G. |
分类号 |
A61K31/502;A61P35/00;C07D237/26 |
主分类号 |
A61K31/502 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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