PHARMACEUTICAL COMPOSITION CONTAINING THIAZIDE-BASED COMPOUND WITH CONTROLLED RELEASE AND ANGIOTENSIN-II-RECEPTOR BLOCKER

摘要

The present invention relates to a pharmaceutical composition in which release of a thiazide-based compound and angiotensin-II-receptor blocker is controlled, and to a combination preparation technique for the same. More particularly, the present invention relates to a preparation technique capable of maximizing pharmacological and clinical blood pressure control effects and complication preventive effects and significantly reducing side effects by administrating a release-controlled combination preparation rather than administrating a single preparation of thiazide-based compound and a single preparation of angiotensin-II-receptor blocker at the same time.