摘要 |
<p>A biomaterial of artificial bone-cartilage complex type can be successfully produced by contacting glycosaminoglycan, proteoglycan and collagen, which are components of a cartilage-like complex, with an artificial bone and allowing the self-organization of the preceding complex based on the preceding artificial bone. This complex type biomaterial is a biomaterial that is usable in reconstructing a joint tissue with the integration of the bone tissue, i.e., the skeleton and the cartilage tissue side, i.e., the movable face of the joint in any bone-cartilage lesion accompanied by the degeneration or fracture of joint such as rheumatoid arthritis, degenerative joint disease, bone fracture, bone tumor and so on.</p> |