发明名称 NEUROFILAMENTAL PROTEINS AS BIOMARKER FOR ALZHEIMER'S DISEASE
摘要 <p>The present invention relates to a method for assessing Alzheimer's disease in vitro comprising measuring in a sample (e.g. body fluid) the level of one or more proteins of the group consisting of Neurofilament triplet M protein and Alpha-internexin, or a variant thereof, wherein an altered level of said one or more proteins, or a variant thereof, is indicative that said individual suffers from Alzheimer's Disease. Furthermore, the present invention relates to a method for monitoring the progression of the Alzheimer's disease in vitro comprising measuring in a sample (e.g. body fluid) the level of one or more proteins of the group consisting of Neurofilament triplet M protein and Alpha- internexin, or a variant thereof, wherein an altered level of said one or more proteins, or a variant thereof, compared with an earlier measurement of the level of said one or more proteins, or a variant thereof, is indicative for the progression of Alzheimer's disease.</p>
申请公布号 WO2008148492(A8) 申请公布日期 2009.11.05
申请号 WO2008EP04237 申请日期 2008.05.28
申请人 F. HOFFMANN-LA ROCHE AG;BERNDT, PETER;BOHRMANN, BERND 发明人 BERNDT, PETER;BOHRMANN, BERND
分类号 G01N33/68 主分类号 G01N33/68
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