BIODEGRADABLE MATRIX MATERIALS

摘要

The invention provides biodegradable degradable matrix materials. The matrix materials of the invention are useful in a variety of applications such as to make implantable medical devices (e.g., implants, coatings, in-situ formed matrices, stents, tubes, aneurysm coils, and the like), in-situ delivery (e.g., cell delivery or bioactive agent delivery), and as tissue sealants. In many embodiments, the matrix materials of the invention are formed by reacting: (a) a first component comprising an aminated natural degradable polysaccharide with (b) a second component comprising an amine-reactive compound.