发明名称 |
MICROORGANISMS FOR THE PRODUCTION OF METHACRYLIC ACID |
摘要 |
The invention provides a non-naturally occurring microbial organism having a 2- hydroxyisobutyric acid, 3-hydroxyisobutyric acid or methacrylic acid pathway. The microbial organism contains at least one exogenous nucleic acid encoding an enzyme in a 2- hydroxyisobutyric acid, 3-hydroxyisobutyric acid or methacrylic acid pathway. The invention additionally provides a method for producing 2-hydroxyisobutyric acid, 3-hydroxyisobutyric acid or methacrylic acid. The method can include culturing a 2-hydroxyisobutyric acid, 3- hydroxyisobutyric acid or methacrylic acid producing microbial organism expressing at least one exogenous nucleic acid encoding a 2-hydroxyisobutyric acid, 3-hydroxyisobutyric acid or methacrylic acid pathway enzyme in a sufficient amount and culturing under conditions and for a sufficient period of time to produce 2-hydroxyisobutyric acid, 3-hydroxyisobutyric acid or methacrylic acid. |
申请公布号 |
CA2722680(A1) |
申请公布日期 |
2009.11.05 |
申请号 |
CA20092722680 |
申请日期 |
2009.04.30 |
申请人 |
GENOMATICA, INC. |
发明人 |
BURK, MARK J.;BURGARD, ANTHONY P.;OSTERHOUT, ROBIN E.;PHARKYA, PRITI |
分类号 |
C12N1/21;C12N1/00;C12N9/00;C12N15/00;C12N15/52;C12P7/40 |
主分类号 |
C12N1/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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