<p>The invention provides a synthetic route from sarsasapogenin to timosaponin BII and related compounds.A diketone intermediate is provided, which can advantageously be used for in situ assembly of complex sugar moieties of the desired glycone end product. The diketone compound is then selectively reduced using a borohydride reducing agent to form the desired end product, certain of the end products and intermediates are novel compounds perse.</p>
申请公布号
WO2009132478(A1)
申请公布日期
2009.11.05
申请号
WO2008CN00889
申请日期
2008.04.30
申请人
PHYTOPHARM PLC;INSTITUTE OF RADIATION MEDICINE, ACADAEMY OF MILITARY MEDICAL SCIENTCES OF THE PLA;CHENG, SHUIHONG;DU, YUGUO;MA, BAIPING;LI,LU;ZHAO, YANG
发明人
CHENG, SHUIHONG;DU, YUGUO;MA, BAIPING;LI,LU;ZHAO, YANG