| 发明名称 |
Substituted oxoazaheterocyclyl compounds |
| 摘要 |
This invention is directed to oxoazaheterocycyl compounds which inhibit Factor Xa, to oxoazaheterocycyl compounds which inhibit both Factor Xa and Factor IIa, to pharmaceutical compositions comprising these compounds, to intermediates useful for preparing these compounds, to a method of directly inhibiting Factor Xa and to a method of simultaneously directly inhibiting Factor Xa and Factor IIa.
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| 申请公布号 |
US7612075(B2) |
申请公布日期 |
2009.11.03 |
| 申请号 |
US20030628093 |
申请日期 |
2003.07.25 |
| 申请人 |
AVENTIS PHARMACEUTICALS INC. |
发明人 |
EWING WILLIAM R.;BECKER MICHAEL R.;CHOI-SLEDESKI YONG MI;PAULS HEINZ W.;HE WEI;CONDON STEPHEN M.;DAVIS RODERICK S.;HANNEY BARBARA A.;SPADA ALFRED P.;BURNS CHRISTOPHER J.;JIANG JOHN Z.;MYERS MICHAEL R.;LAU WAN F.;LI AIWEN;POLI GREGORY B.;BOBKO MARK A.;MORRIS ROBERT L.;KARPINSKI JOSEPH M.;GALLAGHER TIMOTHY F.;NEUENSCHWANDER KENT W.;GRONEBERG ROBERT D.;SABUCO JEAN-FRANCOIS |
| 分类号 |
A61K31/497;C07D401/12;A61K31/495;A61K31/496;A61K31/517;A61P7/02;A61P9/10;A61P19/02;A61P25/28;A61P35/00;A61P43/00;C07D241/08;C07D401/06;C07D401/14;C07D403/06;C07D405/14;C07D409/06;C07D409/12;C07D409/14;C07D413/14;C07D417/14;C07D471/04;C07D495/04;C07D519/00 |
主分类号 |
A61K31/497 |
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