PHARMACEUTICAL FORMULATION

摘要

PURPOSE: A pharmaceutical formulation containing atorvastatin and irbesartan is provided to effectively prevent and treat hypertension, hyperlipidemia and their complication. CONSTITUTION: A pharmaceutical formulation of which release is controlled comprises a immediate release compartment containing atorvastatin as a pharmacologically active ingredient, its pharmaceutically acceptable salt, or its isomer, and a sustained release compartment containing irbesartan as pharmacologically active ingredient, its pharmaceutically acceptable salt or its isomer. The sustained release compartment contains osmosis controlling agent and is coated with semi-permeable coating substrate. The pharmaceutical formulation is used in the form of matrix.