发明名称 |
Vaccine for prevention and treatment of HIV-infection |
摘要 |
This invention relates to novel HIV polypeptide and polynucleotide fusions of Gag, Pol and Nef which are useful in immunogenic compositions and vaccines. The invention relates in particular to a polypeptide which comprises Nef or an immunogenic fragment thereof, and p17 Gag and/or p24 Gag or immunogenic fragments thereof, wherein when both p17 and p24 Gag are present there is at least one HIV antigen or immunogenic fragment between them. The polypeptide may also comprise Pol or RT or an immunogenic fragment thereof.
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申请公布号 |
US7612173(B2) |
申请公布日期 |
2009.11.03 |
申请号 |
US20050573128 |
申请日期 |
2005.08.03 |
申请人 |
GLAXOSMITHKLINE BIOLOGICALS, S.A. |
发明人 |
ABRECHT HELGE;DELCHAMBRE MARTINE;MARCHAND MARTINE;MATHY NATHALIE LOUISE;PERMANNE PHILIPPE JEAN GERVAIS GHISLAIN;VOSS GERALD HERMANN |
分类号 |
C07K14/00;C07K14/16 |
主分类号 |
C07K14/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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