发明名称 |
COMPOUNDS HAVING ANTIMYCOBACTERIAL ACTIVITY |
摘要 |
Novel pyrrole derivatives of formula (I)and their pharmaceutically acceptable acid addition salts having superior antimycobacterial activity against clinically sensitive as well as resistant strains of Mycobacterium tuberculosis as well as having lesser toxicity compared to known compounds. The use of the novel compounds of formula (I) for treatment of latent tuberculosis including Multi Drug Resistant Tuberculosis (MDR TB). The methods for preparation of the novel compounds, pharmaceutical compositions containing the novel compounds and method of treating MDR TB by administration of compounds of formula (I). |
申请公布号 |
EA012461(B1) |
申请公布日期 |
2009.10.30 |
申请号 |
EA20050000500 |
申请日期 |
2002.09.20 |
申请人 |
LUPIN LIMITED |
发明人 |
ARORA SUDERSHAN, KUMAR;SINHA NEELIMA;JAIN SANJAY;UPADHAYAYA RAM, SHANKAR;JANA GOURHARI;AJAY SHANKAR;SINHA RAKEH, KUMAR |
分类号 |
C07D207/32;A61K31/4025;A61P31/06;C07D207/335;C07D401/04;C07D401/12;C07D401/14;C07D403/04;C07D403/12;C07D405/12;C07D405/14;C07D417/06 |
主分类号 |
C07D207/32 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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