| 发明名称 |
Nitrooxy derivatives of losartan, valsartan, candesartan, telmisartan, eprosartan and olmesartan as angiotensin-II receptor blockers for the treatment of cardiovascular diseases |
| 摘要 |
Disclosed are compounds of the formula R-(Y-ONO2)s, where s is 1 or 2, R is an angiotensin II receptor blocker residue of formula (II) or (III), and the remaining substituents are as defined in the specification. The compounds are useful in the treatment of cardiovascular diseases.
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| 申请公布号 |
NZ544463(A) |
申请公布日期 |
2009.10.30 |
| 申请号 |
NZ20040544463 |
申请日期 |
2004.07.20 |
| 申请人 |
NICOX S.A. |
发明人 |
ALMIRANTE, NICOLETTA;DEL SOLDATO, PIERO;ONGINI, ENNIO |
| 分类号 |
A61K31/4178;A61K31/41;A61K31/4184;A61P7/02;A61P9/12;A61P29/00;C07D235/20;C07D257/04;C07D403/04;C07D403/10;C07D409/06 |
主分类号 |
A61K31/4178 |
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