发明名称 HIGH AFFINITY MELAN-A T-CELL RECEPTORS
摘要 The present invention relates to T-cell receptors T(CRs ) having an affinity (K) of less than or equal to 3 μM, and/or an off-rate (k) of 1x10Sor slower, for the AAGIGILTV-HLA-A*0201 complex. Such TCRs are useful, either alone or associated with a therapeutic agent, for targeting cancer cells presenting that complex.
申请公布号 EA012507(B1) 申请公布日期 2009.10.30
申请号 EA20070002677 申请日期 2006.05.31
申请人 IMMUNOCORE LIMITED 发明人 JAKOBSEN BENT, KARSTEN;LIDDY NATHANIEL, ROSS
分类号 C07K14/705;C07K14/725 主分类号 C07K14/705
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