| 摘要 |
The present invention provides compounds of formula (I), their use as an inhibitor of a p53-MDM2 interaction as well as pharmaceutical compositions comprising said compounds of formula (I) wherein n, m, p, s, t, R, R, R, R, R, R, R, X, Y, Q and Z have defined meanings. |
| 申请人 |
JANSSEN PHARMACEUTICA N.V. |
发明人 |
LACRAMPE JEAN, FERNAND, ARMAND;MEYER CHRISTOPHE;LIGNY YANNICK, AIME, EDDY;CSOKA IMRE, CHRISTIAN, FRANCIS;VAN HIJFTE LUC;ARTS JANINE;SCHOENTJES BRUNO;WERMUTH CAMILLE, GEORGES;GIETHLEN BRUNO;CONTRERAS JEAN-MARIE;JOUBERT MURIEL |
