| 摘要 |
Disclosed is a combination consisting essentially of a synergistic amount of an alpha-2-delta ligand and a dual serotonin-noradrenaline re-uptake inhibitor (DSNRI) or a selective noradrenaline re-uptake inhibitor (SNRI), or pharmaceutically acceptable salts thereof, wherein: the alpha-2-delta ligand is Pregabalin, the SNRI is S,S-reboxetine, and the DSNRI is selected from venlafaxine, venlafaxine metabolite O-desmethylvenlafaxine, clomipramine, clomipramine metabolite desmethylclomipramine, duloxetine, milnacipran, and imipramine. These combinations are suitable for use in the treatment of pain, particularly neuropathic pain. |
