发明名称 |
LOW DENSITY LIPOPROTEIN RECEPTOR-MEDIATED SIRNA DELIVERY |
摘要 |
The invention provides interfering RNA molecule-ligand conjugates useful as a delivery system for delivering interfering RNA molecules to a cell in vitro or in vivo. The conjugates comprise a ligand that can bind to a low density lipoprotein receptor (LDLR) or LDLR family member. Therapeutic uses for the conjugates are also provided. |
申请公布号 |
WO2009065022(A3) |
申请公布日期 |
2009.10.29 |
申请号 |
WO2008US83614 |
申请日期 |
2008.11.14 |
申请人 |
ALCON RESEARCH, LTD.;CHATTERTON, JON E. |
发明人 |
CHATTERTON, JON E. |
分类号 |
A61K47/48;A61K31/7088;A61P27/02;C12N15/11 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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