摘要 |
Disclosed is a novel compound having NPY Y5 receptor antagonist activity, specifically a compound represented by formula (I), a pharmaceutically acceptable salt thereof, or a solvate of the compound or the salt. [In the formula, R1 represents a substituted or unsubstituted alkyl or the like; R2 represents a hydrogen, or a substituted or unsubstituted alkyl; ring A represents a monocyclic or bicyclic aromatic heterocycle; R3 represents a substituted or unsubstituted aryl, a substituted or unsubstituted heteroaryl, or a substituted or unsubstituted heterocyclyl; R4 represents a halogen, a cyano, a substituted or unsubstituted alkyl, a substituted or unsubstituted cycloalkyl or the like; m represents an integer of 0-2; n represents an integer of 0-5; R represents a halogen, an oxo, a cyano, a substituted or unsubstituted alkyl or the like; and p represents an integer of 0-2.]
|
申请人 |
SHIONOGI & CO., LTD. |
发明人 |
SAKAGAMI, MASAHIRO;HASHIZUME, HIROSHI;TANAKA, SATORU;OKUNO, TAKAYUKI;YARI, HIROSHI;TONOGAKI, KEISUKE;KOUYAMA, NAOKI |