| 发明名称 |
NUCLEIC ACIDS ENCODING A RECEPTOR FOR IL-17 HOMOLOGOUS POLYPEPTIDES |
| 摘要 |
The present invention is directed to novel polypeptides having sequence identity with IL-17, IL-17 receptors and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided herein are methods for treating degenerative cartilaginous disorders and other inflammatory diseases.
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| 申请公布号 |
US2009269844(A1) |
申请公布日期 |
2009.10.29 |
| 申请号 |
US20030458573 |
申请日期 |
2003.06.10 |
| 申请人 |
GENENTECH, INC. |
发明人 |
CHEN JIAN;FILVAROFF ELLEN;FONG SHERMAN;GODDARD AUDREY;GODOWSKI PAUL;GRIMALDI J. CHRISTOPHER;GURNEY AUSTIN;LI HANZHONG;HILLAN KENNETH;HYMOWITZ SARAH G.;TUMAS DANIEL;STAROVASNIK MELISSA A.;VANLOOKEREN MENNO;VANDLEN RICHARD;WATANABE COLIN;WILLIAMS P. MICKEY;WOOD WILLIAM I.;YANSURA DANIEL |
| 分类号 |
C12N5/06;C07H21/04;C07K14/47;C07K16/18;C12N1/19;C12N1/21;C12N9/00;C12N15/00;C12N15/11;C12P21/02 |
主分类号 |
C12N5/06 |
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