发明名称 |
ANTITUMOR COMBINATION COMPRISING A MORPHOLINYL ANTHRACYCLINE DERIVATIVE AND DEMETHYLATING AGENTS |
摘要 |
The present invention provides a combination of a morpholinyl anthracycline derivative, in particular a methoxy morpholino doxorubicin derivative, or a pharmaceutically acceptable salt thereof, and a demethylating agent, having an antineoplastic effect. Also provided is the use of the said combinations in the treatment or prevention of metastasis, in the treatment of tumors, as well for reversing the resistance in cells resistant to such a methoxy morpholino doxorubicin derivative. |
申请公布号 |
WO2009106549(A3) |
申请公布日期 |
2009.10.29 |
申请号 |
WO2009EP52237 |
申请日期 |
2009.02.25 |
申请人 |
NERVIANO MEDICAL SCIENCES S.R.L.;GERONI, MARIA CRISTINA;VALOTA, OLGA;BROGGINI, MASSIMO |
发明人 |
GERONI, MARIA CRISTINA;VALOTA, OLGA;BROGGINI, MASSIMO |
分类号 |
A61K45/06 |
主分类号 |
A61K45/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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