COMPOUNDS AND METHODS FOR IMPROVING CELLULAR UPTAKE OF OLIGOMERIC COMPOUNDS
摘要
The present invention provides method of optimizing the efficacy and potency of antisense drugs. In certain embodiments, the invention provides assays useful for determining favorable oligonucleotide characteristics and excipeints for improved cellular uptake.
申请公布号
WO2009046426(A3)
申请公布日期
2009.10.29
申请号
WO2008US78956
申请日期
2008.10.06
申请人
ISIS PHARMACEUTICALS, INC.;KOLLER, ERICH;BENNETT, C., FRANK
