发明名称 |
NOVEL FIVE-MEMBERED RING COMPOUND |
摘要 |
<p>Disclosed is a five-membered ring compound represented by formula (1) or a pharmaceutically acceptable salt thereof. The compound inhibits infiltration of leukocytes including eosinophils and lymphocytes, and is effective as a drug for treating various inflammations. The compound is highly safe and can be administered for a long period. A pharmaceutical product containing the five-membered ring compound or a pharmaceutically acceptable salt thereof is also disclosed. (In the formula, R1 represents a halogen atom or a phenyl group which may be substituted by a C1-C3 alkyl group or a C1-C3 alkoxy group; R2 represents a C1-C3 alkylene group which may be substituted by a C1-C3 alkyl group or a carbonyl group; R3 represents a C1-C3 alkyl group; R4 and R5 independently represent a hydrogen atom or a C1-C3 alkyl group, or -N(R4)R5 may represent a morpholino group which may be substituted by a C1-C3 alkyl group; Y2 represents a C2-C4 alkylene group; and R6 represents a hydrogen atom, a halogen atom, a C1-C3 alkyl group or a C1-C3 alkoxy group.)</p> |
申请公布号 |
WO2009131171(A1) |
申请公布日期 |
2009.10.29 |
申请号 |
WO2009JP58054 |
申请日期 |
2009.04.23 |
申请人 |
DAINIPPON SUMITOMO PHARMA CO., LTD.;FUJITA, HITOSHI;KANAI, TOSHIO;IMAI, SATOKI |
发明人 |
FUJITA, HITOSHI;KANAI, TOSHIO;IMAI, SATOKI |
分类号 |
A61P11/06;A61P17/00;A61P17/04;A61P19/02;A61P25/00;A61P27/14;A61P29/00;A61P35/04;A61P37/02;A61P37/06;A61P37/08;A61P43/00;C07D277/42;C07D417/10;C07D277/20;A61K31/426;A61K31/5377;A61P1/04;A61P3/10;A61P11/00;A61P11/02 |
主分类号 |
A61P11/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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