发明名称 1' -substituted carba-nucleoside analogs for antiviral treatment
摘要 Provided are pyrrolo[1,2-f][1,2,4]triazinyl, imidazo[1,5-f][1,2,4]triazinyl, imidazo[1,2-f][1,2,4]triazinyl, and [1,2,4]triazolo[4,3-f][1,2,4]triazinyl nucleosides, nucleoside phosphates and prodrugs thereof, wherein the 1′position of the nucleoside sugar is substituted. The compounds, compositions, and methods provided are useful for the treatment of Flaviviridae virus infections, particularly hepatitis C infections.
申请公布号 AU2009240642(A1) 申请公布日期 2009.10.29
申请号 AU20090240642 申请日期 2009.04.22
申请人 GILEAD SCIENCES, INC. 发明人 OLIVER L. SAUNDERS;LIJUN ZHANG;THOMAS BUTLER;CHOUNG U. KIM;AESOP CHO;JAY PARRISH
分类号 C07D487/04;A61K31/395;A61K31/41;A61K31/4188;A61K31/7052;A61P31/12;C07H19/23 主分类号 C07D487/04
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