发明名称 Method of Screening for the Presence of a Genetic Defect Associated With Deep Venous Thrombosis
摘要 The present invention relates to a method for screening an individual for the presence in his/her genome of a genetic marker that is indicative of an increased risk of deep venous thrombosis, wherein the genetic marker is haplotype 2 of the fibrinogen gamma gene (FGG-H2) as given in FIG. 5A. The genetic marker comprises a set of one, two, three or four mutations in the nucleic acid material encoding fibrinogen gamma, the mutations being selected from the group consisting of 129A/T (rs2066854), 7874G/A (rs2066861), 9615C/T (rs2066864) and 10034C/T (rs2066865).
申请公布号 US2009269738(A1) 申请公布日期 2009.10.29
申请号 US20060887495 申请日期 2006.03.31
申请人 发明人 BERTINA ROGIER MARIA;ROSENDAAL FRITS R.;WILLIGE SHIRLEY UITTE DE;DE VISSER-VAN SOEST MARIA CATHARINA HENRICA;VOS HANS LUUK
分类号 C12Q1/68 主分类号 C12Q1/68
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