LINKER CONTAINING BUNGAROTOXIN AND A BINDING PEPTIDE

摘要

The invention relates to a method for preparing a targetable drug comprising an active compound and a targeting moiety, comprising providing a binding pair consisting of the bungarotoxin (BTX) protein as a first member and a peptide comprising the bungarotoxin-binding site as a second member of said binding pair; (b) providing said active compound with either said first or second member of said binding pair to provide a modified active compound; (c) providing said targeting moiety with the complementary member of said binding pair to provide a modified targeting moiety, and (d) allowing said modified active compound to bind to said modified targeting moiety by contacting said first and second members of said binding pair, thereby providing the targetable drug.