发明名称 |
NANOSTRUCTURES SUITABLE FOR SEQUESTERING CHOLESTEROL AND OTHER MOLECULES |
摘要 |
Articles, compositions, kits, and methods relating to nanostructures, including those that can sequester molecules such as cholesterol, are provided. Certain embodiments described herein include structures having a core-shell type arrangement; for instance, a nanoparticle core may be surrounded by a shell including a material, such as a lipid bilayer, that can interact with cholesterol and/or other lipids. In some embodiments, the structures, when introduced into a subject, can sequester cholesterol and/or other lipids and remove them from circulation. Accordingly, the structures described herein may be used to diagnose, prevent, treat or manage certain diseases or bodily conditions, especially those associated with abnormal lipid levels. |
申请公布号 |
WO2009131704(A2) |
申请公布日期 |
2009.10.29 |
申请号 |
WO2009US02540 |
申请日期 |
2009.04.24 |
申请人 |
NORTHWESTERN UNIVERSITY;MIRKIN, CHAD, A.;THAXTON, C., SHAD;GILJOHANN, DAVID, A.;DANIEL, WESTON |
发明人 |
MIRKIN, CHAD, A.;THAXTON, C., SHAD;GILJOHANN, DAVID, A.;DANIEL, WESTON |
分类号 |
A61K9/127;A61K31/7088;A61P9/10 |
主分类号 |
A61K9/127 |
代理机构 |
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