| 发明名称 |
Constructs for delivery of therapeutic agents to neuronal cells |
| 摘要 |
A non-toxic polypeptide, for delivery of a therapeutic agent to a neuronal cell, comprises a binding domain that binds to the neuronal cell, and a translocation domain that translocates the therapeutic agent into the neuronal cell, wherein the translocation domain is not a HN domain of a clostridial toxin and is not a fragment or derivative of a HN domain of a clostridial toxin.
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| 申请公布号 |
US2009269361(A1) |
申请公布日期 |
2009.10.29 |
| 申请号 |
US20070798909 |
申请日期 |
2007.05.17 |
| 申请人 |
SHONE CLIFFORD CHARLES;SUTTON JOHN MARK;SILMAN NIGEL |
发明人 |
SHONE CLIFFORD CHARLES;SUTTON JOHN MARK;SILMAN NIGEL |
| 分类号 |
A61K39/395;C12N15/09;A61K31/711;A61K35/76;A61K38/00;A61K38/43;A61K47/48;A61K48/00;A61P25/00;A61P25/08;A61P25/16;A61P25/28;A61P31/00;A61P31/18;A61P35/00;C07K14/33;C07K14/34;C12N9/02;C12N9/52;C12N15/62;C12N15/87 |
主分类号 |
A61K39/395 |
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