发明名称 |
Diagnostic And Therapeutic Epitope, And Transgenic Plant |
摘要 |
A peptide analogue which is not more than 50 amino acids in length, and which is capable of being recognized by a T cell receptor that recognizes an epitope comprising sequence 62PQPELPY68 (SEQ ID NO:1), and fusion proteins, pharmaceutical compositions, and kits comprising the same, are provided herewith. Also provided are methods of diagnosing coeliac disease, or susceptibility to coeliac disease, in an individual comprising contacting a sample from the individual with a peptide analogue and determining in vitro whether T cells in the sample recognize the peptide analogue.
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申请公布号 |
US2009269285(A1) |
申请公布日期 |
2009.10.29 |
申请号 |
US20060556208 |
申请日期 |
2006.11.03 |
申请人 |
ANDERSON ROBERT PAUL;HILL ADRIAN VIVIAN;JEWELL DEREK PARRY |
发明人 |
ANDERSON ROBERT PAUL;HILL ADRIAN VIVIAN;JEWELL DEREK PARRY |
分类号 |
A01H5/00;A61K49/00;A01H5/10;A01K67/027;A61K38/08;A61K38/10;A61K38/16;A61K39/00;A61K45/00;A61P1/00;A61P37/06;A61P37/08;A61P43/00;C07K7/06;C07K7/08;C07K14/00;C07K14/415;C12N15/82;C12Q1/02;G01N33/15;G01N33/50;G01N33/53;G01N33/564 |
主分类号 |
A01H5/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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