摘要 |
<p>The present invention is directed to compounds of formula (I)-(II) and pharmaceutically acceptable salts, esters, and prodrugs thereof which are inhibitors of syk and/or JAK kinase. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition syk and/or JAK kinase activity, methods of inhibition the platelet aggregation, and methods to prevent or treat a number of conditions mediated at least in part by syk and/or JAK kinase activity, such as undesired thrombosis and Non Hodgkin's Lymphoma.</p> |
申请人 |
PORTOLA PHARMACEUTICALS, INC.;SONG, YONGHONG;XU, QING;BAUER, SHAWN, M.;JIA, ZHAOZHONG, J.;MEHROTRA, MUKUND;PANDEY, ANJALI |
发明人 |
SONG, YONGHONG;XU, QING;BAUER, SHAWN, M.;JIA, ZHAOZHONG, J.;MEHROTRA, MUKUND;PANDEY, ANJALI |