| 发明名称 |
SCREENING METHODS FOR COMPOUNDS USEFUL IN THE REGULATION OF BODY WEIGHT |
| 摘要 |
The present invention relates to drug screening assays, and diagnostic and therapeutic methods for the treatment of body weight disorders, such as obesity, anorexia and cachexia, utilizing the melanocortin 4-receptor (MC4-R) as the target for intervention. The invention also relates to compounds that modulate the activity or expression of the MC4-R, and the use of such compounds in the treatment of body weight disorders. |
| 申请公布号 |
EP0915706(B1) |
申请公布日期 |
2009.10.28 |
| 申请号 |
EP19970929878 |
申请日期 |
1997.06.09 |
| 申请人 |
MILLENNIUM PHARMACEUTICALS, INC. |
发明人 |
LEE, FRANK;HUSZAR, DENNIS;GU, WEI |
| 分类号 |
A61K38/16;G01N33/50;A61K38/00;A61K38/17;A61K39/395;A61K45/00;A61K48/00;A61P3/04;A61P43/00;C07H21/04;C07K14/72;C12N15/09;C12N15/11;C12Q1/25;C12Q1/66;C12Q1/68;G01N33/15;G01N33/53;G01N33/74 |
主分类号 |
A61K38/16 |
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