发明名称 Compounds having a potentiating effect on the activity of ethionamide and uses thereof
摘要 The present invention relates to the use of compounds with a potentiating effect on the activity of antibiotics that are activatable via the EthA enzymatic pathway, for the preparation of a medicament for preventing and/or treating mycobacterial infections such as tuberculosis and leprosy, to pharmaceutical compositions comprising them in combination with an antibiotic that is activatable via the EthA pathway, to compounds having a potentiating effect on the activity of antibiotics that are activatable via the EthA enzymatic pathway, to pharmaceutical compositions comprising them and to their use as medicaments, especially medicaments for preventing and/or treating mycobacterial infections such as tuberculosis and leprosy.
申请公布号 ZA200810703(B) 申请公布日期 2009.10.28
申请号 ZA20080010703 申请日期 2008.12.19
申请人 INSTITUT PASTEUR DE LILLE;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE;UNIVERSITE DE LILLE 2;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) 发明人 BENOIT DEPREZ;NICOLAS WILLAND;BERTRAND DIRIE;PATRICK TOTO;VINCENT VILLERET;CAMILLE LOCHT;ALAIN BAULARD
分类号 A61K;C07K 主分类号 A61K
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