THERMO SENSITIVE HYDROGEL CONTAINING ANIONIC POLYMERS AND CATIONIC POLYMERS

摘要

PURPOSE: A thermo sensitive hydrogel containing anionic polymers and cationic polymers is provided, which improves engraft capability of the various cell like a chondrocyte. CONSTITUTION: A thermo sensitive hydrogel is thermo sensitivity type hydrogel by the static attraction of the anionic polymer and cationic polymer which have the bio compatibility. The anionic polymer is the carboxymethyl cellulose and has viscosity of 50-3,000 cP. The cationic polymer is more than one kind selected from polyethyleneimine, sparteine, spermidine, spermine, phenylpropanolamine, triethanolammine, epinephrine, and serotonin and has the molecular weight of 10-60,000 g/mol.