| 摘要 |
The invention provides novel kinase inhibitors that are useful as therapeutic agents for example in the treatment malignancies where the compounds have the general formula I wherein A, X, Y, Z, Ra, Rb, Rc, R1, R2, R3 and m are defined herein. |
| 申请人 |
GENENTECH, INC., F. HOFFMANN-LA ROCHE, AG |
发明人 |
RAWSON, THOMAS E;SAFINA, BRIAN;DOTSON, JENNAFER;ALIAGAS-MARTIN, IGNACIO;HALLADAY, JASON;LIANG, JUN;RUETH, MATTHIAS;ZHU, BING-YAN;BROOKFIELD, FREDERICK;PRIME, MICHAEL;ZHANG, BIRONG;LI, JUN M;ZHOU, AIHE |
