发明名称 |
Methods for producing surfaces that resist non-specific protein binding and cell attachment |
摘要 |
<p>A method is disclosed herein for treating a polymeric surface to resist non-specific binding of biomolecules and attachment of cells. The method includes the steps of: imparting a charge to the polymeric surface to produce a charged surface; exposing the charged surface to a nitrogen-rich polymer to form a polymerized surface; exposing the polymerized surface to an oxidized polysaccharide to form an aldehyde surface; and exposing the aldehyde surface to a reducing agent. Advantageously, a method is provided which produces surfaces that resist non-specific protein binding and cell attachment and that avoids the use of photochemical reactions or prior art specially designed compounds.</p> |
申请公布号 |
EP1750130(B1) |
申请公布日期 |
2009.10.28 |
申请号 |
EP20060118370 |
申请日期 |
2006.08.03 |
申请人 |
BECTON, DICKINSON & COMPANY |
发明人 |
CHEN, XIAOXI;GALBRAITH, WILLIAM |
分类号 |
G01N33/543 |
主分类号 |
G01N33/543 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|