发明名称 |
Peptide-chelate conjugates |
摘要 |
A peptide-chelate conjugate with affinity for the ST receptor is disclosed, wherein the chelate is tetradentate. The peptide-chelate conjugate of the invention may be labelled with a radiometal to provide a metal complex. A radiopharmaceutical composition comprising the metal complex is provided. which is suitable for the diagnostic imaging of colorectal cancer. Also provided for in the invention is a kit for the preparation of the radiopharmaceutical preparation.
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申请公布号 |
US7608242(B2) |
申请公布日期 |
2009.10.27 |
申请号 |
US20040469801 |
申请日期 |
2004.12.10 |
申请人 |
GE HEALTHCARE LIMITED |
发明人 |
CUTHBERTSON ALAN;MENDIZABAL MARIVI;DIXON MARK;STOREY ANTHONY E.;BACON EDWARD R.;DESAI VINAY CHANDRAKANT;KASINA SUDHAKAR;WOLFE HENRY RAPHAEL |
分类号 |
A61K51/00;A61K51/08;A61M36/14;C07K5/083;C07K7/00;C07K7/06;C07K14/245;G01N33/574 |
主分类号 |
A61K51/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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