PROCESS FOR THE PREPARATION OF 9-AMINO SUBSTITUTED 9,10-DIHYDROPYRROLO[2,1-B][1,3]BENZOTHIAZEPINES

摘要

A process is described for the preparation of compounds with the following formula where the groups are as defined below, in particular, R1 is a substituted amine, said process includes essentially the reaction of pyrrolobenzothiazep in- 9-one with amine R1H to give the corresponding enamine, which is subsequently transformed into the final compound.