INFUSION DEVICES AND METHOD

摘要

Devices and methods for performing improved percutaneous myocardial revascularization (PMR) procedures. One device includes a preassembled PMR drug delivery catheter and a drug neutraliting vial. The vial assembly allow s prepping the PMR catheter by flushing drug through distal needle, and into a vial cavity where the drug is neutralized by a neitralizing agent. One set o f devices includes needles having protrusions secured to the distal regions of drug delivery tubes. One needle has outward protruding barbs engaging the inner tube wall while another needle has outward threads which can screw int o the tube wall. Radiopaque marker bands are also included in the present invention which are asymmetrically distributed on the catheter shaft, allowi ng a treating physician to determine under fluoroscopy whether the catheter distal region is pointed away or toward the treating physician, as well as determining whether the catheter distal region is rotated toward or away fro m the treating physician. PMR devices include catheter having dual injection needles, for both injecting a drug into the heart wall and a radiopaque contrast media to mark the already treated sites. One PMR injection device h as multiple stops for allowing controlled, variable needle depth penetration wi th a single distal needletip.