发明名称 Sensitization of chemotherapeutic agent resistant neoplastic cells with a virus
摘要 The present invention relates to a method of increasing the sensitivity of neoplastic cells to chemotherapeutic agents by using a virus, a method of treating proliferative disorders with a virus and chemotherapeutic agents, and a method for preventing a neoplasm from developing drug resistance to chemotherapeutic agents. The virus is preferably a reovirus.
申请公布号 US7608257(B2) 申请公布日期 2009.10.27
申请号 US20070809293 申请日期 2007.05.31
申请人 ONCOLYTICS BIOTECH INC. 发明人 COFFEY MATTHEW C.;THOMPSON BRADLEY G.
分类号 A61K39/15;A61K45/00;A61K31/136;A61K31/138;A61K31/17;A61K31/282;A61K31/337;A61K31/407;A61K31/4164;A61K31/513;A61K31/519;A61K31/675;A61K31/704;A61K33/24;A61K35/76;A61K38/21;A61P1/00;A61P1/16;A61P1/18;A61P5/00;A61P7/00;A61P11/00;A61P13/08;A61P13/12;A61P15/00;A61P25/00;A61P25/02;A61P35/00;A61P35/02;A61P35/04;C12N15/18 主分类号 A61K39/15
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