发明名称 |
Expanding the eukaryotic genetic code |
摘要 |
This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided.
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申请公布号 |
US7608423(B2) |
申请公布日期 |
2009.10.27 |
申请号 |
US20070710672 |
申请日期 |
2007.02.22 |
申请人 |
THE SCRIPPS RESEARCH INSTITUTE |
发明人 |
CHIN JASON W.;CROPP T. ASHTON;ANDERSON J. CHRISTOPHER;SCHULTZ PETER G. |
分类号 |
C12P21/00;C07H21/04;C12N;C12N9/16;C12N9/22;C12N15/00;C12N15/10;C12P21/02;C12P21/06;C12Q1/68 |
主分类号 |
C12P21/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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