发明名称 Phenylacetic acid compounds
摘要 The present invention provides a process for the preparation 6-[3-(hetero)aryloxy-2-fluoro-benzyl]-2H-pyridazin-3-one compounds 1 where R2 is an optionally substituted aryl or an optionally substituted heteroaryl, R6 is NO2, NH2, alkyl, halogen, or a function group readily derived therefrom and R4c is hydrogen or alkyl. There also is provided a process for the preparation of phenylacetic acid compounds 2, wherein R2 and R6 are as defined previously and R5a is hydrogen or alkyl, which are useful for the preparation of pyridazinone compounds.
申请公布号 US7608731(B2) 申请公布日期 2009.10.27
申请号 US20070977262 申请日期 2007.10.23
申请人 ROCHE PALO ALTO LLC 发明人 KERTESZ DENIS JOHN;MARTIN MICHAEL;PALMER WYLIE SOLANG
分类号 C07C205/00;C07C205/56;C07C235/46;C07C255/54;C07D209/08;C07D213/65;C07D237/02;C07D237/14;C07D401/12;C07D403/12 主分类号 C07C205/00
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