发明名称 AGENTS USEFUL FOR REDUCING AMYLOID PRECURSOR PROTEIN AND TREATING DEMENTIA AND METHODS OF USE THEREOF
摘要 The present invention provides compounds and methods of administering compounds to a subject taht can reduce .beta.APP production and that is not toxic in a wide range of dosages. The present invention also provides non-carbamate compounds and methods of administering such compounds to a subject that can reduce .beta.APP production and that is not tocix in a wide range of dosages. It has been discovered that either the racemic or enantiomerically pure non-carbamate compounds can be used to decrease .beta.APP production.
申请公布号 CA2465534(C) 申请公布日期 2009.10.27
申请号 CA20012465534 申请日期 2001.11.02
申请人 MESSAGE PHARMACEUTICALS, INC.;THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SE CRE;BROSSI, ARNOLD;SONCRANT, TIMOTHY T. 发明人 BROSSI, ARNOLD;SHAW, KAREN T. Y.;INGRAM, DONALD K.;SONCRANT, TIMOTHY T.;UTSUKI, TADA;STURGESS, MICHAEL;GIORDANO, ANTHONY;DAVIDSON, DIANE;POWERS, GORDON;HOLLOWAY, HAROLD W.;YU, QIANG-SHENG;GREIG, NIGEL H.
分类号 C07D487/04;A61K31/325;A61K31/343;A61K31/345;A61K31/381;A61K31/382;A61K31/403;A61K31/405;A61K31/407;A61K31/5365;A61P25/28;C07C217/58;C07C233/22;C07C265/12;C07D209/16;C07D209/34;C07D209/36;C07D209/38;C07D277/82;C07D453/04;C07D471/04;C07D487/08;C07D491/04;C07D495/04;C07D498/04 主分类号 C07D487/04
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