发明名称 A NEW PROCESS FOR THE MANUFACTURING OF THE COMPOUND 2-HYDROXY-3-[5-(MORPHOLIN-4-YLMETHYL)PYRIDIN-2-YL]1H-INDOLE-5-C ARBONITRILE 701.
摘要 <p>The present invention relates to a new process for the manufacture of the compound 2-hydroxy-3-[5-(morpholin-4-ylmethyl)pyridin-2-yl]1H-ind ole-5-carbonitrile as a free base and pharmaceutically acceptable salts thereof, particularly the 2-hydroxy-3-[5-(morpholin-4-ylmethyl)pyridin-2-yl]1H-ind ole-5-carbonitrile citrate, and to new intermediates prepared in said process suitable for large scale manufacturing of said compound.</p>
申请公布号 MX2009010890(A) 申请公布日期 2009.10.26
申请号 MX20090010890 申请日期 2008.04.17
申请人 ASTRAZENECA AB 发明人 MARTIN HEDBERG;VERN DELISSER;ANNETTE JANSSON;ANDREAS RAADEVIK;PER RYBERG;SWANTJE THIERING
分类号 C07D401/04;A61K31/5355;C07D213/38 主分类号 C07D401/04
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