摘要 |
A method for the differential diagnosis of hyperaldosteronism in the ischemic heart disease and the chronic heart insufficiency comprises radioimmunoassay of aldosterone in blood plasma and the measurement of renin activity. Furthermore, adrenocorticotropic hormone (ACTH) is assayed. When aldosterone content exceeds 150 pg/mL (control value 136.9±12.7 pg/mL), ACTH content exceeds 65 pg/mL control value 57.3±7.6 pg/mL) and rennin activity is within or below control values (5.7±0.6 ng/mL/h), hyperaldosteronism of central genesis is diagnosed. When ACTH content is within the control values and rennin activity exceeds 6.3 ng/mL/h, hyperaldosteronism of peripheral genesis is diagnosed. When ACTH content and rennin activity are augmented relative to control values, the mixed genesis of hyperaldosteronism is evident. |