发明名称 DEUTERIUM BEARING ANALOGS OF ANASTROZOLE AS AROMATASE INHIBITORS FOR THE TREATMENT OF BREAST CANCER
摘要 <p>This invention relates to novel, substituted aralkyl heterocyclic compounds according to formula I, their derivatives, pharmaceutically acceptable salts thereof. This invention also provides compositions comprising a compound of this invention and the use of such compositions in methods of treating diseases and conditions that are beneficially treated by administering aromatase inhibitors. Formula (I), or a pharmaceutically acceptable salt thereof, wherein: each R1 is independently selected from CH3, CH2D, CHD2 or CD3; each R2 is independently selected from CH3, CH2D, CHD2 or CD3; each Y is independently selected from H or D; and when each R variable is CH3, at least one Y is D.</p>
申请公布号 WO2009128919(A1) 申请公布日期 2009.10.22
申请号 WO2009US02354 申请日期 2009.04.15
申请人 CONCERT PHARMACEUTICALS, INC.;HARBESON, SCOTT, L. 发明人 HARBESON, SCOTT, L.
分类号 C07D249/08;A61K31/4196;A61P35/00 主分类号 C07D249/08
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