发明名称 |
TRICYCLIC ANTIBIOTICS |
摘要 |
<p>The invention relates to antibacterial compounds of formula (I) wherein U represents CH or N; W represents CH or N; R1 represents alkoxy, halogen or CN; ring A represents a pyrrolidin-l,3-diyl-, a piperidin-l,3-diyl or a morpholin-2,4-diyl group and B represents CH2; or ring A is selected from the groups drawn below:formula (II) wherein R2 represents H, F or hydroxymethyl, and B is absent; G represents a group selected from the group consisting of -CH=CH-E,formula (III) and formula (IV) wherein Y1, Y2, Y3 and Z independently represent CH or N; Q represents O or S; and E represents phenyl which is mono- or di-substituted wherein the substituents are each independently halogen; and to pharmaceutically acceptable salts of such compounds.</p> |
申请公布号 |
WO2009128019(A1) |
申请公布日期 |
2009.10.22 |
申请号 |
WO2009IB51541 |
申请日期 |
2009.04.14 |
申请人 |
ACTELION PHARMACEUTICALS LTD;HUBSCHWERLEN, CHRISTIAN;RUEEDI, GEORG;SURIVET, JEAN-PHILIPPE;ZUMBRUNN ACKLIN, CORNELIA |
发明人 |
HUBSCHWERLEN, CHRISTIAN;RUEEDI, GEORG;SURIVET, JEAN-PHILIPPE;ZUMBRUNN ACKLIN, CORNELIA |
分类号 |
C07D491/048;A61K31/33;A61P31/04;C07D519/00 |
主分类号 |
C07D491/048 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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