发明名称 |
METHODS OF STIMULATING AN IMMUNE RESPONSE AGAINST PROSTATE SPECIFIC ANTIGEN |
摘要 |
The invention provides a prostate specific antigen oligo-epitope peptide (PSA-OP) that is useful as an immunogen in the prevention or treatment of prostatic cancer and in the inhibition of prostatic cancer cells and in the establishment and characterization of PSA-specific cytotoxic T-cell lines. In particular, the invention provides methods for eliciting an immune response against PSA comprising administering (i) a priming inoculation of a first recombinant virus encoding PSA-OP and (ii) one or more boosting inoculations of a second recombinant virus encoding PSA-OP, wherein the first and second recombinant viruses are from a different genus.
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申请公布号 |
US2009263425(A1) |
申请公布日期 |
2009.10.22 |
申请号 |
US20090479292 |
申请日期 |
2009.06.05 |
申请人 |
HUMAN SERVICE |
发明人 |
SCHLOM JEFFREY;TSANG KWONG-YOK;ZAREMBA SAM |
分类号 |
A61K39/275;A61K35/12;A61K38/00;A61K39/00;A61P35/00;C07H21/04;C07K14/82;C12N5/0783;C12N9/64;C12N15/57;C12Q1/68 |
主分类号 |
A61K39/275 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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