发明名称 |
METHODS AND COMPOSITIONS FOR TREATING POST-OPERATIVE PAIN COMPRISING A LOCAL ANESTHETIC |
摘要 |
The present invention is directed to an implantable drug depot useful for reducing, preventing or treating post-operative pain in a patient in need of such treatment, the implantable drug depot comprising a polymer and a therapeutically effective amount of a local anesthetic or pharmaceutically acceptable salt thereof, wherein the drug depot is implantable at a site beneath the skin to reduce, prevent or treat post-operative pain, and the drug depot is capable of releasing (i) a bolus dose of the local anesthetic or pharmaceutically acceptable salt thereof at a site beneath the skin and (ii) a sustained release dose of an effective amount of the local anesthetic or pharmaceutically acceptable salt thereof over a period of at least 4 days. |
申请公布号 |
CA2700736(A1) |
申请公布日期 |
2009.10.22 |
申请号 |
CA20092700736 |
申请日期 |
2009.04.17 |
申请人 |
WARSAW ORTHOPEDIC, INC.;MEDTRONIC, INC. |
发明人 |
KING, VANJA MARGARETA;HOBOT, CHRISTOPHER M.;BIGGS, DR. DANIELLE;SHAW, KATARA;WOHABREBBI, AMIRA;MCKAY, WILLIAM F.;MCDONALD, PHILLIP EDWARD |
分类号 |
A61K31/4458;A61K9/20;A61K47/34;A61P29/00 |
主分类号 |
A61K31/4458 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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